DOWN: multiple uses [advanced]

Verb apply maximum effort and concentration
Scientists bear down, attacking H7N9 on multiple fronts. They are testing wild birds and thousands of domestic fowl, analyzing the viruses they find, and trying to trace people who have been exposed to infected patients.
Verb take strong steps to enforce rules
In an attempt to crack down on writers manipulating their reviews, Amazon is deleting thousands from its site. A debate is now percolating over what it means to review and to what standards they should be held.
Verb totally enjoy oneself
get down
Watch Snowball, the dancing cockatoo, get down to music. He has the beat and amazing dance moves too!
Phrase apply oneself
3D learning tools are proving to be positive for pupils, helping children to knuckle down more according to a new study conducted in schools across Europe.
Verb leave active work or service
stand down
Pope Benedict stunned the Roman Catholic Church when he announced he would stand down, the first pope to do so in 700 years, saying he no longer had the mental and physical strength to carry on.
Verb overcame by facing head on
The stars aligned in New York. Andy Murray stared down fatigue and history and wind and doubt, elevating his play when it mattered most to beat Novak Djokovic and capture the Grand Slam title.
Verb give up or retire from a position
His career as a competitive athlete already in shambles from a doping scandal, Lance Armstrong announced he would step down as the chairman of his cancer foundation, Livestrong.
Phrase draw gradually toward an end
While Twinkies have a reputation for an unlimited shelf life, the company that makes the junk food may not. Hostess Brands said on Friday that it planned to wind down its operations.